The article is devoted to the assessment of interconnection and interaction problems of an individual and a collective. The different definitions of personality are analyzed. There has been made a historical excursus to the theory of collective development during the soviet and post-Soviet period. There also have been set forth the views of interconnection and interaction of individual and a collective of outstanding pedagogues A. S. Makarenko and I. P. Ivanov. The modern psycho-pedagogical analysis of these theories confirms its actuality (...) and practical importance. (shrink)

Malignant cells are characterized by an increased content of endogenous formaldehyde formed as a by‐product of biosynthetic processes. Accumulation of formaldehyde in cancer cells is combined with activation of the processes of cellular formaldehyde clearance. These mechanisms include increased ALDH and suppressed ADH5/FDH activity, which oncologists consider poor and favorable prognostic markers, respectively. Here, the sources and regulation of formaldehyde metabolism in cancer cells are reviewed. The authors also analyze the participation of oncoproteins such as fibulins, FGFR1, HER2/neu, FBI‐1, and (...) MUC1‐C in the control of genes related to formaldehyde metabolism, suggesting the existence of two mutually exclusive processes in cancer cells: 1) production and 2) oxidation and elimination of formaldehyde from the cell. The authors hypothesize that the study of the anticancer properties of disulfiram and alpha lipoic acid – which affect the balance of formaldehyde in the body – may serve as the basis of future anticancer therapy. (shrink)

Монография предназначена для специалистов в области социальной философии, социологии и истории, а также для широкого круга читателей.

t. 1. Vlastʹ kli︠u︡cheĭ -- t. 2. Na vesakh Iova.

для научных работников, преподавателей, аспирантов, студентов юридических вузов и факультетов.

Издание адресовано научным работникам, преподавателям, студентам и аспирантам, а также практикам, интересующимся вопросами истории философии, эстетики, религиоведения и смежными проблемами.

The controversies in Bristol, Alder Hey and elsewhere in the UK surrounding the removal and retention of human tissue and organs have led to extensive law reform in all three UK legal systems. This paper reports a short study of the reactions of a range of health professionals to these changes. Three main areas of ethical concern were noted: the balancing of individual rights and social benefit; the efficacy of the new procedures for consent; and the helpfulness for professional practice (...) of the new legislation and regulation. Recognition of these concerns may help in forging a new partnership between professionals and patients and their families. (shrink)

Книга представляет собой исследование, где предпринимается попытка на основе детальной проработки первоисточников и воспроизведения основных ходов мысли и интуиций Гегеля и позднего Шеллинга провести сравнительный анализ их учений об абсолюте.

Packing optimization problems have a wide spectrum of real-word applications. One of the applications of the problems is problem of placement of containers with spent nuclear fuel on the storage platform. The solution of the problem can be reduced to the solution of the problem of finding the optimal placement of a given set of congruent circles into a multiconnected domain taking into account technological restrictions. A mathematical model of the prob-lem is constructed and its peculiarities are considered. Our approach (...) is based on the mathematical modelling of rela-tions between geometric objects by means of phi-function technique. That allowed us to reduce the problem solving to nonlinear programming. Today, an important scientific problem is the problem of creating conditions for safe storage of spent nuclear fuel. In the process of creating any dry spent nuclear fuel storage, the following main stages can be identified: site selection, storage design, construction, operation and decommissioning. A full check for compliance of the repository and its elements with these standards usually begins at the design stage. At the stage of site selection, the inspection for compliance with safety standards is carried out only in terms of the impact of the repository as a whole on the environment. This approach cannot be considered fully appropriate, because, taking into account, for example, all the climatic features of the future storage site, it is possible to adjust the thermal storage regimes of spent nuclear fuel. Similarly, it can be considered necessary to analyze and select the shape of the storage site in order to accommo-date the maximum possible number of spent fuel containers. Such a choice, obviously, should be made taking into ac-count the norms of nuclear, radiation and thermal safety, as well as in compliance with technological limitations. The problem of finding the optimal placement of containers taking into account the given technological limitations can be formulated in the form of the problem of optimization of geometric design. Therefore, the purpose of the study is to build a mathematical model of the problem and study its characteristics to develop effective methods of solution. The proposed approach is based on mathematical modeling of relations between geometric objects using the method of phi-functions. This allowed to reduce the solution of the problem to the problem of nonlinear programming. (shrink)

Background:Altering components of ecological momentary assessment (EMA) measures to better suit the purposes of individual studies is a common and oftentimes necessary step. Though the inherent flexibility in EMA has its benefits, no resource exists to provide an overview of the variability in how convergent constructs and symptoms have been assessed in the past. The present study fills that gap by examining EMA measurement design for mood and anxiety symptomatology.Methods:Various search engines were used to identify 234 relevant studies. Items administered, (...) data collection schedules (i.e., beeps per day), response scales (i.e., Likert), data collection platforms (i.e., apps), and psychometric properties (i.e., reliability) were extracted.Results:Study designs varied greatly in all aspects across the identified papers. Over 4,600 extracted items were qualitatively analyzed, resulting in the identification of 12 themes. The most EMA items focused on affect, with categories such as “happiness” and “tension” appearing most frequently. We provide all of our data extraction in the format of an open-source database.Limitations:Despite our best attempts to include as much of the relevant literature as possible, this review and the accompanying database are not exhaustive, but can easily be built upon to include other, newer studies.Conclusions:The fact that the affect theme featured both positive and negative emotional constructs highlights the dichotomous focus on valence and affect within the literature surrounding anxious and depressive symptomatology. We hope that our database will act as a helpful design decision-making resource for researchers studying this kind of symptomatology in the future.Systematic Review Registration:PROSPERO (CRD42019139409). (shrink)

Prior studies have reported that women outperform men in nonverbal communication, including the recognition of emotions through static facial expressions. In this experimental study, we investigated sex differences in the estimation of states of happiness, anger, fear, and disgust through static photographs using a two-culture approach. This study was conducted among the Tuvans and Mongolian people from Southern Siberia. The respondents were presented with a set of photographs of men and women of European and Tuvan origin and were asked to (...) interpret each of them. They were asked: “What does the person in the photo feel?” We found that the Tuvans easily identified happiness and anger; however, the level of accuracy of fear and disgust recognition was low. No sex differences in the recognition of happiness, disgust, and fear were observed. However, anger recognition was significantly moderated by the perceiver’s sex and the origin of the model. Compared to Tuvan men, Tuvan women were significantly less accurate in identifying anger in male Tuvans. Furthermore, the age effect was found in recognition of fear: older Tuvans were more accurate while recognizing the fearful faces of Tuvan, but not the European models. (shrink)

The aim of the research is to elucidate the key notions of the German mystic thinker Jacob Boehme’s linguistic-philosophical theory: language of Nature (Natursprache), Adamic language and sensual language in regard to each other and to post-Babel historical languages of humankind. This theory is considered in a dual context of the Late Renaissance “Adamicist” studies and of Boehme’s theosophical project as a whole. Since a considerable part of his work had a form of an extensive commentary on Genesis, Boehme’s interpretations (...) of the biblical stories are devoted to linguistic topics. Explaining the stories concerning Babel (Gen. 11), the theosophist gives some considerations to the essence of historic transformation and loss of the primordial language. Based on the story of Adam’s naming of the animals (Gen. 2:19–20), Boehme formulates his views on the substance of Natural and Adamic languages. It is argued that, according to the theosophist, the rise of polyglottism, caused by Babel catastrophe, was a culmination of spiritual disorientation of humankind. Having started from the Fall, that process led to a fundamental distortion of ideas about being and the Deity. Due to this, people decided to look for Him in a reified form by technical means. A cognitive and linguistic aspect of that disorientation consisted in alienating of still single primordial language from Natursprache as its ontological foundation. Boehme thought that this alienation mainly caused rapid development of linguistic pluralism. Meanwhile, the language of Nature was a unique “guide,” which made possible for Adam to create his epistemically perfect language, and his descendants could keep its understanding for some time. (shrink)

The Clauser–Horne approach used to derive experimentally measurable quantities for performing experiments on EPR paradox based on Type-I Spontaneous Parametric Down Conversion (SPDC) sources is discussed. It is proved that in this case the deduced Bell's type inequality does not correctly express separability and causality. A deeper analysis of the problem shows that the Clauser–Horne hypothesis of factorizability of joint detection probability cannot be considered so general as to describe this physical situation.

Our journal is now a half century old. ... For those who have been associated with Voprosy filosofii all these years the time, it seems, has passed quickly. I remember how we celebrated the twenty-fifth anniversary of the journal and the plans we made then. It seems that all this happened quite recently. But if one now recalls what happened with our journal and our philosophy in general during these years, one gets the uncanny feeling that we have lived through (...) several lives with Voprosy filosofii, very intense and dramatic lives, each continuing the preceding one and at the same time somehow quite different from it. (shrink)

Antonio Argandoña, Norbert Bilbeny, Victòria Camps, Miquel Calsina, Àngel Castiñeira, Cristian Palazzi, Ferran Requejo, Raimon Ribera, Begoña Román, Ferran Sàez, Miquel Seguró, Francesc Torralba, Josep Maria Vallès, Rosamund Thomas Ramon Llull Journal of Applied Ethics 2012 3(3):9-16.

In the not-too-distant past, the activity approach was quite popular in Russian philosophy and in many human sciences, including psychology. Recently it has come under criticism, even from some of its former proponents. This issue begins a series of articles devoted to assessing the results of research that has been conducted in Russia along the lines of this approach. The authors of the articles are philosophers, psychologists, and educational theoreticians and practitioners.

In the history of culture there are "linking" themes, a common interest in which sometimes brings quite distant periods closer together. One such theme that affects the contemporary understanding of medieval culture is, in our view, the problem of speech and silence as types of relation to reality based, respectively, on its intelligible differentiation and its total acceptance as such.

Coming fromI andCl, i.e. from intuitionistic and classical propositional calculi with the substitution rule postulated, and using the sign to add a new connective there have been considered here: Grzegorozyk's logicGrz, the proof logicG and the proof-intuitionistic logicI set up correspondingly by the calculiFor any calculus we denote by the set of all formulae of the calculus and by the lattice of all logics that are the extensions of the logic of the calculus, i.e. sets of formulae containing the axioms (...) of and closed with respect to its rules of inference. In the logiclG the sign is decoded as follows: A = (A & A). The result of placing in the formulaA before each of its subformula is denoted byTrA. The maps are defined (in the definitions of x and the decoding of is meant), by virtue of which the diagram is constructed. (shrink)

IntroductionExperimental research on animals has been guided by principles of the three Rs: reduction, refinement and replacement.1 Recently the fourth R—rehabilitation—has also been incorporated to enhance the welfare of animals that are used in research. With growing scientific curiosity and increasing research, animal use has anything but reduced despite the fact that modern technology has brought to fore many alternatives to animal use.2 ,3 There are many arguments for and against animal use. In India, there has been a proposal to (...) ban the use of animals for training and academic purposes, as reported in two major daily newspapers. This has evoked mixed reactions from the scientific community. We conducted this study to assess the awareness, attitudes and practices regarding the use of animals and their alternatives, in medical training and research amongst medical teachers and students.Study designA …. (shrink)